Jameson Holden

No posts

Measuring Illusions with Brain Gauge: The Connectivity Score

In a previous report, we discussed how an illusory conditioning stimulus could be context dependent and that frequently delivering repetitive stimuli has the effect of suppressing the percept of a stimulus. Repeat a stimulus many times (the conditioning stimuli that are delivered by the Brain Gauge are typically sinusoidal at a frequency that delivers many repeats to the same place on the finger tip) and the effect is that stimuli feel much smaller. Are there other illusions? The obvious answer is yes, since we’re writing this report. The illusion


For some, a concussion is a temporary inconvenience. For others, the effects can be long lasting.

Neurophysiological deficits detected over one year post-concussion
Even though the water swirls the opposite direction down under, it looks like concussed brains in Australia look like concussed brains in North America; regardless of how long it has been since someone’s last concussion, it’s hard to hide neurophysiological changes that persist from the Brain Gauge methods. Dr. Alan Pearce of the University of Melbourne recently presented some very interesting data at an international meeting in Toronto. In his study, he made observations on individuals from three different groups: post-concussion


Does new technology always improve precision and accuracy?

Reaction time is one of the most frequently collected and depended upon metrics for cognitive assessment – but most methods are extremely inaccurate. The Brain Gauge is the world’s most accurate commercially available device that can deliver the reaction time test.

It seems like there is a constant and steady improvement in technology and computing power. The cell phones that we carry now have exponentially more computational power than computers that we (I speak for the people in my generation) were programming in the late 1970s and early 1980s. However,


Measuring Illusions with Brain Gauge

Tactile illusions can be measured and in this example, the results inform us about plasticity.
Most people are familiar with optical illusions. For example, the one shown here is a context dependent illusion. Glancing at the two sets of circles, it appears that the center circle of the cluster on the left is larger than the center circle of the cluster on the right. But in fact, the two center circles are of equal size. Why does the brain trick you into thinking this? Part of the answer is that


An Oldie but a Goodie – the Reaction Time Test

Reaction time has been used since the mid-1800s to assess cognitive function, and it is still useful for that today.
The reaction time test has been used for a really long time to investigate nervous system function. Papers written as early as the mid 1800’s describe the reaction time test and since that time, most papers focused on differences in reaction time and other populations. In other words, most of these papers demonstrated comparisons that were made between healthy control populations and populations of individuals that had some condition


Effects of Alcohol on College-Age Brains

Results of our study demonstrate that 18-22 year olds that drink excessively have diminished plasticity.

We conducted a study on college-aged subjects (age 18-22) to assess the impact of their drinking behavior on cortical metrics scores. The study involved testing a large number of individuals in that age range and having them answering questionnaires about their drinking behavior. Interestingly (as an aside), the regulatory oversight committee did not want to approve the study at first because they claimed that the study was assuming that individuals under the age of 21


The Impact of Cough Syrup on Plasticity

Brain Gauge methods are sensitive enough to detect changes in plasticity with a small dose of cough syrup.
Ever take cough syrup and feel a bit strange? And then maybe wonder how it was impacting your brain? It probably did a good job suppressing your cough, but some medications do change the way you think.

One of the studies that we performed over a decade ago investigated the impact of cough syrup on plasticity. Cough syrup – and more specifically DXM (dextromethorphan) – is what is known as an NMDA receptor antagonist.


Stand Up For Better Brain Health

Exercise alone is not the only thing you need to do to insure good brain health. Measuring with the Brain Gauge can make sure that your lifestyle is not impacting your brain health in a negative way.
The link between exercise and brain health is strongly support by research and as recently been widely publicized. We've even written about it on this blog. But what if exercise alone is just a piece of the entire picture of brain health?

A recent study performed by researchers at UCLA reveals the specific


When it comes to nootropics, more isn't always better

Use of the Brain Gauge with the knowledge of a tuning curve will help you optimize brain performance.
Whether it's at work or on the field, humans are constantly looking for ways to get better. But our bodies, just like any machine, needed to be tuned in very specific ways in order to for us to achieve optimal performance. For example, if you want to run a fast marathon, you'll need to put in a lot of long runs and a lot of calories in the months leading up to


Caffeine: The World's Oldest Nootropic

The effects of caffeine on brain function and how to measure it.
Though media outlets often portray 'biohacking' as a hightech, modern trend, people have been searching for ways to improve their brain function for centuries.

Back in the 1400s, Arabian monks first noted the energizing and mood-enhancing effects of hot drinks made from the beans of the coffee tree. However, caffeine - the chemical responsible for coffee's stimulating effects - was not identified until 1819, when the German chemist Friedlieb Ferdinand Runge isolated it from coffee. Since this discovery,


The Safest and Most Effective Nootropic

Exercise can give your brain an immediate boost – we conducted a simple study and report results.
Reaction time (RT) is one of the most common ways to measure brain activity. Simple reaction time - the time elapsed between a stimulus and corresponding response - has been used to assess cognitive function in both healthy and impaired individuals. Reaction time variability (RTvar) - a measure of the standard deviation of reaction time scores - can be used to quantify attention span, and tends to be higher in people with ADHD and


The Brain Gauge: an Effective Tool for Biohackers

Hacking your brain but don't know if it is having an effect? The Brain Gauge can help.
The biohacking community is growing faster than ever. This group of health enthusiasts, collectively known as biohackers, try to hack or modulate their body's abilities by using a variety of supplements, lifestyle changes, and radical diets. Over the past 12 months, brain hacking in particular has become very popular. This division of biohacking tends to prioritize improvements to IQ, focus, memory, and mental stamina. The methods used for brain hacking range from dietary


Find out why biohackers are going nuts for this superfood

Consumption of walnuts appears to have a positive effect on brain health.
Every day, it seems like there's a new “superfood” that promises to boost your brain power or overall health. Recently, walnuts in particular have seen a rise in popularity due to their supposed benefits on cognition and mood. But is there any truth to those claims? A 2015 study by Arab & Ang investigated some of the proclaimed effects of walnut consumption. Subjects were surveyed on their daily intake of nuts and then categorized into 3 groups: walnuts


Why the Brain Gauge works for people of all ages

Cortical metrics stay within normative range for a large age spectrum – as long as people stay healthy.
We often get asked whether age-related declines in skin sensitivity can affect your Brain Gauge scores. This is a legitimate concern, as confounding factors in the peripheral nervous system can invalidate many neurological tests. If peripheral sensory receptors are transmitting weak or noisey signals in response to a certain stimulus, the test will fail to effectively activate the central nervous system. Fortunately, we kept this issue in mind during our research and development,


Is Sleep a Form of Biohacking?

Sleep deprivation will negatively impact your Brain Gauge scores; optimal sleep will optimize your brain health.
One of the most simple and straightforward Brain Gauge tests is the simple reaction time test (RT). This type of test is commonly used as a good “first glance” at overall brain health. In this test, a delayed response time can be a strong indication that there is something unusual happening with your brain. However, this metric is very sensitive to a number of lifestyle factors (such as lack of sleep, medication side effects,


Brain Gauge Concussion Scoring

An introduction to the scoring system with the Brain Gauge.
The results are in! With over 2000 subjects in the concussion study, we have some pretty solid results for you to compare with.

**The Fatigue metric is computed and correlates well with standardized clinical assessments of fatigue that rely on questionnaires.

*TOJ and DD are dependent on location of trauma. TOJ is more likely to deviate from the norm with front of head injury and DD is more likely to deviate with back of head injury. In other words, insult


CAP Corporation has partnered with Cortical Metrics to integrate their award-winning Brain Gauge Technology

CAP corp is an organization founded to prevent concussions.alt

CAP (Concussion Active Prevention) Corporation and Cortical Metrics announced today that they have signed a long-term strategic alliance to realize market opportunities that will utilize their joint assets.

Cortical Metrics has been dedicated to developing objective, quantitative, reliable and efficient assessments of brain performance by merging state-of-the-art engineering and neuroscience. Originally spun out of the University of North Carolina following decades of neuroscientific research, Cortical Metrics works with a large consortium of researchers specializing in neurological disorders.

The integration of Brain


Concussion Study Update

A summary of the results from an ongoing concussion study.


Summary of previous report: Our brain health assessment system is composed of a test device (the Brain Gauge; above) and a number of tests that task different mechanisms of information processing (e.g., lateral inhibition, adaptation, feed-forward inhibition, neuron-glial interactions). The results of these tests are then used to generate an overall performance score (or cortical metric). Sports concussion studies using this technology and protocols have established efficacy for detecting mTBI and tracking its recovery, demonstrating a 99% confidence level


Large Changes to **Pro**Tools coming this week

Announcement of software release for new analysis package.

Major changes to those of you using our ProTools software will be rolling out this week. The software you know and love is largely staying the same, but we have tweaked the way data sessions are viewed with a more efficient and intuitive data timeline. We are dedicated to providing updates to improve our system, and we think you'll find that this new version of ProTools is much faster and more intuitive.



Each data session is now a point


Case study: Promising Results with Pre-Parkinson's Disease

Brain Gauge data from treatment of one of Dr. Phil Schalow’s patients with pre-Parkinson’s

Welcome to Cortical Metrics Insights! This is our long overdue third issue.

We’ve been busy getting ready to launch the Brain Gauge, but meanwhile, there's lots of great news from our users of the Brain Gauge Pro to report on……we’ll do our best to catch up by having several newsletters in the next few weeks.
Last issue, we highlighted Timing Perception and told you which scientific findings related to it.


Improvements in Brain Gauge performance parallel mTBI recover

Brain Gauge data improves in mTBI patient after treatment with Dr. George Roth.

Dr. George Roth has consistently provided reports that demonstrate patient improvement in corticalmetrics post-treatment.

A 40 year old patient suffered direct left parietal head trauma from a motor vehicle collision, and 8 months post-trauma, the patient continued to suffer from cognitive, visual, and vestibular disorders. Patient was also sensitive to light and noise, reported neck pain, and was unable to continue in her post-graduate program. The patient had sustained one previous concussion in 2005.

Cortical Metrics tests


Case Study: NUCCA treatment leads to neurological improvement